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Advanced Migraine Formula
Migraine Formula
Advanced Migraine Formula has proven itself to us to be the most effective natural formula that we have ever found. All the ingredients are scientific-chosen 100% naturals in composition and purity…making Advanced Migraine Formula truly unparalleled in its potency and effectiveness. We are happy to inform you that…more and more patients suffering from migraine headache are finding solution through our Advanced Migraine Formula …is the natural way to help manage your migraine pain.
Key Benifits of taking Advanced Migraine Formula :
MigraineFormula
  • Improving regularity
  • Promote body relaxation
  • Enhancing blood circulation
  • Promote optimum immune function
  • Promote balance chemicals in the brain
  • Ease minor pain
  • Increase energy
  • Promoting over all well-beings
 

Naturally Manage Your Migraine Headaches

Advanced Migraine Formula is the Natural Health Breakthrough Formula that designed to assist your body’s natural managing process. It contains only the finest and scientific confirmed ingredients for their natural effectiveness and purity to bring a real solution to your migraine headaches.

Healthy immune function promotes vibrant health… vitality and energy to get moving…prevent illnesses…and improve over all health.

More than 28 million Americans, three times more women than men, have suffered from migraine headache. Although any head pain can be miserable, a migraine headache is often disabling. A migraine headache is often accompanied by signs and symptoms, such as nausea, vomiting, and extreme sensitivity to light and sound. A migraine pain can be excruciating and may incapacitate you for hours or even days.

SUPPLEMENT FACTS

Serving Size: 2 Capsules
Servings Per Container: 30

Amount Per Serving

% Daily Value

Riboflavin (Vitamin B2)

200mcg

11.64%

Vitamin D (Calciferol)

2000 IU

500,00%

Calcium Citrate

400mg

40,00%

Magnesium carbonate

300mg

56,00%

Proprietary Blend

415.2mg

5HTP

*

Butterbur

*

Feverfew

*

* Daily Value Not Established

OTHER INGREDIENTS

Stearic Acid, Gelatin (capsules)
This product contains no yeast, wheat, corn, dairy, soy, or glutens.

SUGGESTED USE

    • Take 2 capsules 2 times a day on an empty stomach.
    • This product can be taken with food as well.
    • Store in a cool and dry place.
    • Do not exceed more than 4 capsules in one day.
    • This product has a 3 year shelf life.

INTRODUCTIONBack to top

migraine_formulaMore than 28 million Americans, three times more women than men, suffer from migraine headaches, a type of headache that’s often severe.  Although any head pain can be miserable, a migraine headache is often disabling.  In some cases, these painful headaches are preceded  or accompanied by a sensory warning sign (aura), such as flashes of light, blind spots or tingling in the arm or leg. Normal visual field on the left. Visual field with a migraine aura on the right. A migraine headache is also often accompanied by other signs and symptoms, such as nausea, vomiting, and extreme sensitivity to light and sound.  Migraine pain can be excruciating and may incapacitate you for hours or even days.
The right medicines combined with self-help remedies and changes in lifestyle may make a tremendous difference for sufferers. A typical migraine headache attack produces some or all of these signs and symptoms:
Moderate to severe pain.  Many migraine headache sufferers feel pain on only one side of their head, while some experience pain on both sides

  • Head pain with a pulsating or throbbing quality
  • Pain that worsens with physical activity
  • Pain that hinders your regular daily activities
  • Nausea with or without vomiting
  • Sensitivity to light and sound

When left untreated, a migraine headache typically lasts from 4 to 72 hours, but the frequency with which they occur can vary from person to person.Some may have migraines several times a month or just once or twice a year. Not all migraine headaches are the same. Most people suffer from migraines without auras, which were previously called common migraines. Some have migraines with auras, which were previously called classic migraines. If you’re in the second group, you’ll likely have auras about 15 to 30 minutes before your headache begins. They may continue after your headache starts  or even occur after your headache begins.

These may include:

  • Sparkling flashes of light
  • Dazzling zigzag lines in your field of vision
  • Slowly spreading blind spots in your vision
  • Tingling, pins-and-needles sensations in one arm or leg
  • Rarely, weakness or language and speech problems

Whether or not you have auras, you may have one or more sensations of premonition (prodrome) several hours or a day or so before your headache actually strikes, including:

  • Feelings of elation or intense energy
  • Cravings for sweets
  • Thirst
  • Drowsiness
  • Irritability or depression

CAUSES AND TRIGGERS OF MIGRAINES

Although much about headaches still isn’t understood, some researchers think migraines may be caused by functional changes in the trigeminal nerve system, a major pain pathway in your nervous system, and by imbalances in brain chemicals, including serotonin, which regulates pain messages going through this pathway. During a headache, serotonin levels drop.  Researchers believe this causes the trigeminal nerve to release substances called neuropeptides, which travel to your brain’s outer covering. There they cause blood vessels to become dilated and inflamed. The result is headache pain. Because levels of magnesium, a mineral involved in nerve cell function, also drop right before or during a migraine headache, it’s possible that low amounts of magnesium may cause nerve cells in the brain to misfire. Whatever the exact mechanism of headaches, a number of things may trigger them.

COMMON MIGRAINE HEADACHE TRIGGER INCLUDE:

HORMONAL CHANGES

Although the exact relationship between hormones and headaches isn’t clear, fluctuations in estrogen and progesterone seem to trigger headaches in many women with migraine headaches.  Women with a history of migraines often have reported headaches immediately before or during their periods.  Others report more migraines during pregnancy or menopause.  Hormonal medications, such as contraceptives and hormone replacement therapy, also may worsen migraines.

FOODS

Certain foods appear to trigger headaches in some people.  Common offenders include alcohol, especially beer and red wine, aged cheeses, chocolate, fermented, pickled or marinated foods, aspartame, caffeine, monosodium glutamate (a key ingredient in some Asian foods) certain seasonings, and many canned and processed foods.  Skipping meals or fasting also can trigger migraines.

STRESS

A period of hard work followed by relaxation may lead to a weekend migraine headache.  Stress at work or home also can instigate migraines.

SENSORY STIMULUS

Bright lights and sun glare can produce head pain. So can unusual smells including pleasant scents such as perfume and flowers.  Unpleasant odors such as paint thinner and secondhand smoke may also trigger migraines.

PHYSICAL FACTORS

Intense physical exertion, including sexual activity, may provoke migraines. Changes in sleep patterns including too much or too little sleep, also can initiate a migraine headache.

CHANGES IN ENVIRONMENT

A change of weather, season, altitude level, barometric pressure or time zone can prompt a migraine headache.

RISK FACTORS

Many people with migraines have a family history of migraine. If both of your parents have migraines, there’s a good chance you will too. Even if only one parent has migraines, you’re still at increased risk of developing migraines. You also have a relatively higher risk of migraines if you’re young and female. In fact, women are three times as likely to have migraines as men are.  Headaches tend to affect boys and girls equally during childhood but increase in girls after puberty. If you’re a woman with migraines, you may find that your headaches worsen during menstruation. They may also change during pregnancy or menopause.

 

INDIVIDUAL INGREDIENT FUNCTIONS

RIBOFLAVIN (VITAMIN B2)Back to top

riboflavin

Some evidence indicates that impaired mitochondrial oxygen metabolism in the brain may play a role in the pathology of migraine headaches. As the precursor of the two flavin coenzymes (FAD and FMN) required by the flavoproteins of the mitochondrial electron transport chain, supplemental riboflavin has been investigated as a treatment for migraines. A randomized placebo-controlled trial examined the effect of 400 mg of riboflavin/day for 3 months on migraine prevention in 54 men and women with a history of recurrent migraine headaches. Riboflavin was significantly better than placebo in reducing attack frequency and the number of headache days, though the beneficial effect was most pronounced during the third month of treatment.

It should be noted, however, that only about 25 mg of riboflavin can be absorbed in a single oral dose. A more recent study by the same investigators found that treatment with either a medication called a beta-blocker or high-dose riboflavin resulted in clinical improvement, but each therapy appeared to act on a distinct pathological mechanism; beta-blockers on abnormal cortical information processing and riboflavin on decreased brain mitochondrial energy reserve.  Though these findings are preliminary, they suggest that riboflavin supplementation might be a useful adjunct to pharmacologic therapy with beta-blockers in migraine prevention.

VITAMIN D

vitaminD

Vitamin D is a fat-soluble vitamin that is naturally present in very few foods, added to others, and available as a dietary supplement. It is also produced endogenously when ultraviolet rays from sunlight strike the skin and trigger vitamin D synthesis. Vitamin D is essential for promoting calcium absorption in the gut and maintaining adequate  serum calcium and phosphate concentrations to enable normal mineralization of bone and prevent hypocalcemic tetany. It is also needed for bone growth and bone remodeling by osteoblasts and osteoclasts.

Without sufficient vitamin D, bones can become thin, brittle, or misshapen. Vitamin D sufficiency prevents rickets in children and osteomalacia in adults. Together with calcium, vitamin D also helps protect older adults from osteoporosis. Vitamin D deficiency has become a very popular topic in professional literature, and deservedly so. Vitamin D is important not only for bone health, but for normal functioning of many organs. Its deficiency appears to be much more common than it was previously suspected.

A Dr. Steve Wheeler has found vitamin D deficiency in 42% of 55 patients with chronic migraine headaches. He presented these findings at the American Headache Society. The study also showed that the longer individuals had chronic migraine, the more likely they were to be vitamin D deficient. One possible cause of what appears to be increasing incidence of vitamin D deficiency is widespread use of prescription and over-the-counter antacids. Reducing stomach acidity helps relieve heartburn and other symptoms of reflux, but it may also interfere with absorption of vitamins and minerals.

CALCIUM CITRATE

calcium_citrate

Calcium is a mineral that is found naturally in foods. Calcium is necessary for many normal functions of your body, especially bone formation and maintenance. Calcium can also bind to other minerals (such as phosphate) and aid in their removal from the body. Calcium citrate is used to prevent and to treat calcium deficiencies.

Calcium Citrate has been used for many health problems including high cholesterol, high blood pressure, lactose intolerance, migraine headaches, weight loss, etc… Some studies have shown that migraines may be caused due to a dysfunction in calcium ion transport between cell membranes in the brain. Some people that suffer from migraines may inherit one or more factors that impair calcium channels, making them susceptible to headaches. For example, mutations in a gene that encodes calcium channels appears to be responsible for familial hemiplegic migraine.

MAGNESIUM CARBONATE

magnesium

Magnesium levels tend to be lower in those with migraine headaches, including children and teenagers, when compared to those who do not get headaches.  A few studies suggest that taking a magnesium supplement may decrease the length of time that a migraine headache lasts and reduce the amount of medication you need to relieve the pain from  a migraine.

Combining magnesium with the herb feverfew along with vitamin B2 (riboflavin) may be particularly helpful when you have a headache.  This is a welcome alternative for many, especially if you have trouble taking medications because of side effects. However, if you have 3 or more headaches per month, magnesium does not seem to work as well as prescription medications to prevent migraine headaches (that is, reduce their frequency by taking the medication or supplement every day).  Unless, you are a woman and your migraines tend to happen around the time of your menstrual period; then, magnesium can be an effective way to prevent such headaches.  Magnesium sulfate may even be administered intravenously in the hospital if home remedies for the migraine symptoms are not working.

5 HTP (5-HYDROXYTRYPTOPHAN)Back to top

5HTP

5-Hydroxytryptophan or 5-HTP is a naturally-occurring amino acid a precursor to the neurotransmitter serotonin and  an intermediate in tryptophan metabolism.  It is marketed in the U.S. and other countries as a dietary supplement for   use as an antidepressant, appetite suppressant, and sleep aid. 5-HTP has been shown to be a possible effective aid for depression because of its connection to serotonin. It is also used as a prophylactic against migraine headaches. Studies have shown that migraines occur when serotonin levels are low.

BUTTERBUR

buterbur

Butterbur is a traditional herbal treatment for migraine prevention.Two studies have indicated that Butterbur really does reduce the frequency of migraine attacks. The first clinical trial of Butterbur was published in the journal European Neurology in 2004. It was a small trial involving 33 patients randomized to treatment with Butterbur extract or placebo.

Those results were followed by a larger trial involving 245 patients done at The Albert Einstein College of Medicine in New York. In the study, researchers compared the effects of 50 or 75 mg twice a day of Butterbur extract pills vs. a placebo in preventing migraine headaches in 245 people with frequent migraine. All of the participants reported at least two to six migraine headache attacks per month over the previous three months before the study began.

After four months of treatment, researchers found the 75 mg dose reduced migraine headache frequency by 48% vs. the 26% reduction found with the placebo. The 50 mg dose was associated with a 36% reduction in migraine headache frequency, which according to the researchers is not significantly different from the effects of the placebo. Significantly more people in the 75 mg dose group had a 50% reduction in migraine attacks  per month than those receiving the placebo. The most commonly reported side effects of treatment with Butterbur were gastrointestinal problems, predominantly burping. Researchers aren’t quite sure how Butterbur works to prevent migraine headaches, but previous studies have suggested that the herbal extract has anti-inflammatory properties.  Inflammation has been implicated in the cascade of events that trigger a migraine.  The safety of Butterbur was confirmed in previous work in 2003.

FEVERFEW

feverfew

Feverfew (Tanacetum parthenium), a member of the sunflower family, has been used for centuries in European folk medicine as a remedy for headaches, arthritis, and fevers. In fact, the term feverfew is adapted from the Latin word febrifugia or fever reducer. Feverfew has also been traditionally used to treat menstrual irregularities, labor difficulties, skin conditions, stomach aches, and asthma. Today, feverfew is used to treat and prevent certain headaches, arthritis, and other painful disorders. Feverfew gained popularity in Great Britain in the 1980s as an alternative to conventional medications for migraine headaches.

In fact, a survey of 270 migraine sufferers in Great Britain revealed that more than 70% of individuals felt substantially better after ingesting an average of two to three fresh feverfew leaves daily. Since then, several well-designed studies have been conducted to evaluate the safety and effectiveness of feverfew for the prevention and treatment of migraine headaches.  Most of these studies have found beneficial results. For example, in a study of 76 migraine sufferers, those who ingested feverfew capsules (70 to 114 mg) daily for 4 months experienced a 24% reduction in attacks and a substantial drop in symptoms that often accompany migraines, such as nausea and vomiting, compared to those who received placebo.

POSSIBLE INTERACTIONSBack to top

Feverfew can inhibit the activity of platelets (a substance that plays a role in blood clotting), so individuals taking blood-thinning medications (such as aspirin and Warfarin) should consult  a healthcare practitioner before taking this herb.  Feverfew may diminish the effectiveness of non steroidal anti-inflammatories such as Ibuprofen or Aleve.

FORMULA DESCRIPTION

Advanced Migraine Formula is a proprietary blend of all natural ingredients that have been shown to have supportive effects in those persons affected by the migraine syndrome. As we  all know, there is no “cure” for the condition.  The aim of our product is to prevent and minimize the symptoms. Advanced Migraine Formula is not intended for use in the setting of an acute migraine attack. For that, you should see your regular healthcare provider. All of the ingredients in Advanced Migraine Formula have been extensively studied and researched in the medical literature. Each has been shown to be safe and effective for this purpose. Although adverse reactions are possible with any food or medication, the research on our ingredients has shown them to be very safe in this regard.

SUGGESTED USE / HOW SUPPLIED

Advanced Migraine Formula is intended for the prophylaxis of migraine headaches. The literature would indicate that continued daily use for a period of 2 to 3 months in necessary to obtain the full effect of the product. The suggested dose is 2 capsules two times a day on an empty stomach.  It may also be taken with food if desired.  We also advise that you make the best e­ffort to adopt lifestyle and dietary changes that give you the greatest chance of improvement in your symptoms. Please refer to the introductory portion of this monograph for details of those changes. We encourage you to notify your regular healthcare provider of your use of this product. Advanced Migraine Formula is supplied in a gelatin, dye free capsule in bottles of 60 capsules.

STORAGE

Advanced Migraine Formula should be stored at room temperature in a container and a secure location. It should remain stored in its original child proof container. Excesses of temperature and humidity may affect the potency of the product. This product has a 3 year shelf life.

ADVERSE REACTIONS

Those persons taking non steroidal anti-inflammatory drugs such as Advil, Motrin or Aleve, should use Advanced Migraine Formula with caution and be mindful of gastrointestinal symptoms.  As with any food or medication, there is the possibility of an adverse reaction.  If for any reason you believe that is occurring, with this product, stop taking the product and seek advice from your healthcare provider.  Most of these types of adverse reactions will resolve with cessation of the use of the product.

CONTRAINDICATIONS

Advanced Migraine Formula should not be taken by any person with a known hypersensitivity to any of the component ingredients.  Advanced Migraine Formula is contraindicated for use in children under the age of 12 years.  We advise against use by women who are nursing, pregnant or who may become pregnant.  Persons taking certain anticoagulants or antiplatelet agents such as Warfarin, Aspirin or Plavix, should not take Advanced Migraine Formula.

DRUG INTERACTIONS

See adverse reactions and contraindications.

FDA REQUIRED DISCLAIMER

The products and the claims made about specific products on or through this document have not been evaluated by the United States Food and Drug Administration and are not approved to diagnose, treat, cure or prevent disease. The information provided in this brochure is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information in this brochure for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem.

 

 

 

 

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